SALUGENESIS
A Step-by-Step Method to Deliver Personalized Care for Complex Chronic Conditions
Identify the core mechanisms of chronic disease and design personalized lifestyle protocols to reduce disease burden, improve function, and support healthspan.
MD/DO · PA/NP · RDN/Nutritionists · DC · ND · Advanced Health Coaches
Founded in 2013 • Trusted by 10,000+ clinicians
Pathogenesis
Pathogenesis is the study of how disease develops and has been the dominant lens in modern medicine. It’s essential for acute care (e.g., trauma, infection, emergencies) and for identifying and stratifying risk. However, when we apply a pathogenesis-only lens to chronic conditions, care tends to focus on managing disease rather than restoring health.
How this shows up in practice:
- Managing disease labels instead of linking mechanisms & drivers to the person in front of you.
- Organ silos and algorithm tiers that help at the population level, however, do nothing for the individual in front of you.
- Polypharmacy to suppress downstream effects while upstream dynamics persist.
Progression of chronic disease, increasing comorbidities and medications with age, without significant improvements in healthspan.
The reality (stats from the CDC and National Council on Aging):
- 60% of adults live with a chronic disease.
- 40% of children live with a chronic disease.
- 93% of adults over 65 years of age live with a chronic disease.
- 70% of all deaths are secondary to a chronic disease.
Depending on the condition, approximately 40–80% of the chronic disease burden is attributed to modifiable lifestyle factors.
Pathogenesis tells us what went wrong. It does not tell us how to restore health. It’s abundantly clear we need a better way.
Salugenesis
Salugenesis is the body’s natural healing cycle that restores health after an insult (e.g., infection, toxins, hypoxia, trauma).
For a patient to return to health, they must progress through three phases of the healing cycle: inflammation → proliferation → differentiation.
The mitochondria are the primary drivers that enable progression through each of the three phases. Suppose the mitochondria can’t facilitate the transition (e.g., due to active infection, hypoxia/poor perfusion, cofactor deficiencies, cytokine milieu, extracellular ATP). In that case, we observe cellular and molecular changes that contribute to the biology of chronic disease and persistence of symptoms.
In this program, you’ll learn to identify and remove the blocks that prevent a patient from progressing through all three phases, thereby moving the system back toward health and the completion of salugenesis.
Evidence-informed: this framework draws on peer-reviewed literature in Mitochondrion (salugenesis/healing cycle), Biology (Basel) (incomplete healing & aging), PNAS (hypometabolic states/mitochondrial danger signaling), Nature Reviews Molecular Cell Biology (mitochondria as signaling organelles), and Nature Medicine (chronic inflammation in aging / across the lifespan).
Our Approach
A clear, repeatable framework that integrates principles from salugenesis, molecular nutrition, and functional medicine into one coherent, actionable approach.
- Salugenesis: A framework that focuses on restoring health by focusing on cellular and mitochondrial function.
- Molecular nutrition: A branch of nutrition science that integrates molecular biology to explain how nutrients and food-derived bioactives modulate gene expression, protein function, cell signaling, and metabolism, thereby influencing cellular pathways and health phenotypes.
- Functional medicine: A patient-centered, systems-oriented model that tailors care to an individual’s genetics, environment, and lifestyle.
A quick note on functional medicine. The promise is real. However, as popularity has grown, a commercial ecosystem of laboratory and supplement companies has expanded alongside it, and in some settings, can influence patient care. Patients may be advised to spend thousands on broad lab panels and large supplement stacks that clearly aren’t individualized.
Not everyone requires the same therapeutic diet, exercise plan, supplement protocol, or lab work to achieve meaningful outcomes. This is why we favor a more targeted approach:
- Start with the cell. We prioritize restoring mitochondrial and cellular function, as every tissue, organ, and organ system is ultimately comprised of cells.
- Foundations first. Nutrition, exercise, sleep, and stress management all enhance the effectiveness of any treatment. Supplements are individualized, phased, and sparing.
- Personalized testing. Labs should be tailored to each patient’s unique circumstance and timed appropriately.
- Deprescribe low-value care. Reduce pill burden, adverse events, and costs by aligning interventions with the systems biology framework.
- Track what matters. Use objective data, such as biomarkers, functional measures, and patient-reported outcomes, to measure response and inform adjustments.
What this gives:
- Fewer low-yield tests and non-targeted protocols.
- Clear priorities matched to the patient’s context.
- Phase-appropriate lifestyle interventions with measurable progress.
Salugenesis and molecular nutrition deliver on the promise of functional medicine by avoiding common pitfalls, focusing on mitochondrial and cellular drivers of chronic disease, and using individualized testing to guide care.
By the end of the program, you'll be able to:
- Assess metabolic and immune function, taking into account genetic risk, using our clear decision frameworks.
- Prioritize and personalize lifestyle interventions based on your patient’s signs, symptoms, and laboratory results.
- Perform a nutrition-focused physical exam and uncover functional nutritional deficiencies.
- Decide when and how to order clinical labs without shotgun testing.
- Interpret targeted metabolomics, lipidomics, and clinical biomarkers (e.g., glucose regulation, inflammation, endocrine, cardiac, microbial metabolites).
- Personalize therapeutic diets without supplement overload.
- Track objective clinical markers with appropriate follow-up timelines.
Not just more education. Get access to our step-by-step method that unifies three core disciplines into one organized approach you can use at every visit.
The Curriculum
Designed for physicians, physician assistants/associates, nurse practitioners, registered dietitians, nutritionists, naturopathic doctors, doctors of chiropractic, and advanced health coaches managing complex chronic conditions.
This is a structured, asynchronous 12-month program consisting of 58 hours of lecture. You can watch the lectures at your convenience. New modules are released monthly (dates below). You’ll keep lifetime access to all released content—no need to keep up with every release.
Every module ends with an optional exam designed to confirm mastery. Why this helps you (and your patients):
- Accountability: a clear indication that mastery of concepts is achieved.
- Immediate feedback: know why an answer is right or wrong and what to do next.
- Better retention & application: retrieval practice turns concepts into actionable next steps.
- Professional accomplishment: shows academic rigor to colleagues and employers.
You will have lifetime access to the curriculum.
| Module 1: Pillars of Health-Disease Dynamics | 10 Hours |
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In this module, we will build a solid foundation. Master the core concepts of chronic disease so that, as we progress through each module, you can effectively apply them to create a systematic approach for personalized, targeted, whole-person care.
| Module 2: Psychoneuroendocrinology | 4 Hours |
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Uncover how the mind, brain, and hormones co-create health and dysfunction. We’ll discuss the physiology behind trauma and the stress response, along with a stepwise process to recalibrate setpoints to move patients back to a state of resilient health.
We’ll segue into the science behind change, where we’ll develop a simple, patient-centered framework that aligns goals with what matters most to your patient. When the plan feels like it belongs to them, follow-through increases, and lasting change occurs.
| Module 3: The Nutrition-Focused Physical Exam (NFPE) | 2 Hours |
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Learn to link physical exam findings to potential nutritional deficiencies and toxicities, assess functional status, and translate findings into clear interventions.
| Module 4: Molecular and Personalized Nutrition | 5 Hours |
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Learn what to eat, how to eat, and when to eat—then translate it into plans that actually work. We’ll cover macros and calories (made simple), and show you how to design a personalized nutrition plan that restores metabolic flexibility—better energy, body composition, and glycemic control. On the molecular side, you’ll learn to use targeted labs to spot metabolic bottlenecks (mitochondrial efficiency, insulin dynamics, micronutrient gaps), align them with food-first strategies and evidence-based supplementation, and set a clear retest schedule—all without ordering costly, non-targeted panels.
| Module 5: Exercise, Sleep, & Hormesis | 5 Hours |
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Master the physiology behind exercise and sleep, then translate it into care. You’ll learn which modalities fit which patients, how to tailor dosing to individual goals, and how to layer controlled (hormetic) stressors—such as breathwork, cold/heat exposure, fasting, and more—into daily routines that upregulate cellular processes, extend healthspan, and support longevity. We’ll then show you exactly how to maximize sleep for recovery, cognition, and metabolic health.
| Module 6: Bioenergetics and Mitochondrial Dysfunction | 5 Hours |
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See how mitochondrial function and redox balance shape complex chronic illness, learn how ATP is produced and regulated across systems, and spot key bottlenecks with targeted testing—then craft personalized interventions that support progression through salugenesis (the healing cycle).
| Module 7: Cardiometabolic Disease | 5 Hours |
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Understand the drivers behind metabolic syndrome, dyslipidemia, hypertension, MASLD/MASH (formerly NAFLD/NASH), and ASCVD; confirm with targeted testing, and translate findings into personalized lifestyle interventions.
| Module 8: Autoimmunity | 5 Hours |
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Move beyond innate vs. adaptive to a systems biology view of immunity. Understand chronic inflammation, the gut–immune axis, and tolerance vs. dysfunction to identify core pathways involved, allowing us to rethink autoimmunity beyond conventional labels.
| Module 9: Blood Chemistry, Metabolomics, and Lipidomics | 5 Hours |
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Know when advanced labs add value and how to read them in context. Learn to analyze patterns and trends to identify the mechanisms and bottlenecks specific to each patient’s biochemistry.
| Module 10: Nutrigenomics and Nutrigenetics | 5 Hours |
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Utilize nutritional genomics to understand the likelihood of dysfunction and the patient’s response to macronutrients, micronutrients, and food bioactives, along with how genetics impacts sleep and exercise to enhance overall health.
| Module 11: Advanced Nutrition Interventions | 5 Hours |
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Identify when advanced nutrition interventions add value; learn how to assess, implement, and maintain them as short- and long-term strategies.
| Module 12: Capstone: End-to-End Framework | 2 Hours |
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Pull everything together into a repeatable, step-by-step process you can use at every visit to deliver personalized care for complex chronic conditions.
Certificate of Completion
Complete all modules and pass the end-of-module exams to earn a Certificate of Completion for this program.
Use it to document your training and showcase your skills on your CV or LinkedIn, and include it in professional development records.
(Not a license, board certification, or CME; certificate recognizes successful completion of this educational program.)
Free Bonuses for the Upcoming Cohort
We’ve intentionally designed this for the busy clinician. As one of the first cohorts in our brand-new program, you will have additional perks that will not be available to future cohorts:
- Monthly custom lectures centered around your specific questions.
- Lifetime access to the recordings of the custom cohort lectures.
Once a month, after a new module is released, you can submit any questions you have about the lecture that has been released. We’ll review every submission and create a new recorded lecture tailored to the cohort, addressing the most commonly asked questions in lecture format.
Each lecture is then uploaded to your dashboard, with timestamps and a searchable archive. This format provides the added benefit of learning from the questions your colleagues might pose. It also removes the hassle of coordinating your schedule to join a live session (often difficult to do for the busy clinician).
As a reminder, you’ll receive lifetime access to the curriculum. You’ll also get lifetime access to the monthly cohort recordings. This way, there’s no rush to get through the material. You’ll also have the ability to go back and review as often as you need.
You’ll also get a complimentary 1:1 onboarding session focused on helping you get the most from the program. We’ll show you exactly where to get your questions answered and how to use the tools, resources, and replays—so you build momentum fast. This will be scheduled via Zoom at a mutually agreeable time.
About Your Instructor
Andrew Reid
- Bachelor of Science in Biology, California State University Dominguez Hills, 2010
- Physician Assistant Program, University of California Davis, 2012
- Master of Science in Physician Assistant Studies, AT Still University, 2013
- Master of Science in Personalized Nutrition, University of Connecticut, 2025
- Graduate Certificate in Precision Nutrition, University of Connecticut, 2025
I founded Medgeeks in 2013 to help student clinicians excel on exams and rotations, which naturally evolved into mentoring practicing primary-care clinicians. In 2021, when my daughter was born, everything refocused. By six months, a mitochondrial mutation had unfolded into multiple complex chronic conditions—showing me firsthand where reductionist care falls short.
I shifted to a systems biology, molecular medicine lens: linking mechanisms to presentations, prioritizing cellular health, and using targeted testing to identify modifiable drivers. That data shaped a personalized plan anchored in lifestyle interventions—and it changed her trajectory. Today she’s a healthy, happy toddler.
Salugenesis distills this approach into practical, evidence-informed frameworks that help clinicians identify and prioritize what matters most. My promise is to equip you with tools that enhance clarity, minimize distractions, and support whole-person, personalized care.
Frequently Asked Questions
Enrollment to Salugenesis Closed
What’s included:
- 12-month curriculum — 58 hours of step-by-step lectures.
- Complimentary 1:1 onboarding — quick orientation to get the most from the program.
- Private Salugenesis community — ask questions and get support.
- Monthly custom lectures — new sessions created from member questions.
- Slide decks for every lecture — ready to reference or print.
- Audio-only versions — learn on the go.
- Digital textbooks — beautifully designed companions for each module.
- End-of-module exams — check understanding and track progress.
- Certificate of completion — document your learning.
Enrollment for our program, Salugenesis, is currently closed.
In the meantime, join our free masterclass on personalizing care for chronic disease; you’ll also be added to the waitlist and be the first to know when enrollment reopens.